PREPARATION AND CHARACTERIZATION OF BONDED-PHASES OF CALIXARENE-SULFONYL-CARBOXAMIDES IN PARTIAL-CONE CONFORMATION FOR DETERMINATION OF SALBUTAMOL IN LIVESTOCK BY NANO-MEDIATED BONDED-PHASES: NANO-BASKETS OF CALIXARENE IN PARTIAL-CONE CONFORMATION

a new sensitive method for determination of salbutamol, as a nutrient repartitioning agent, in livestock is presented to protect the consumers. eight nano-baskets of p-tert-calix[4]arene bearing di-[n-(x)sulfonyl carboxamide] and di-(1-propoxy) in partial-cone conformation were synthesized and were used to prepare bended phases of hplc-uv. the new synthesized bonded-phases were characterized and optimized, the bonding interactions of solute and stationary phases were examined and the main interactions were reported. the results revealed that for the best bonded-phase, the lod and loq were 0.02 and 0.06 μg/ml, respectively.